At times, human intervention is needed for interspecies gene transfer because the hybrid embryo is unable to mature and sprout. Thus, the hybrid embryo is removed quickly and placed in a tissue-culture where it can reach maturity. This embryo rescue technique allows genes to be transferred from distant, incompatible relatives through intermediate, mildly compatible relatives of both donor and recipient species.
Adapted from: Safety of Genetically Engineered Foods Approaches to Assessing Unintended Health Effects, Institute of Medicine and National Research Council of the National Academies, 2004, The National Academy Press
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