In interspecies crossing, portions of chromosomes from distant species are recombined via chromosomal translocation. This chromosome engineering referred to as nonrecombinant deoxyribonucleic acid (rDNA) cytogenetic manipulations, is a limiting technique. This is because large portions of chromosomes are transferred in this process including the “bad “genes. Therefore, this method is becoming more competitive with rDNA technology whereby smaller portions of chromosomes, containing the genes of interests, are transferred.
Adapted from: Safety of Genetically Engineered Foods Approaches to Assessing Unintended Health Effects, Institute of Medicine and National Research Council of the National Academies, 2004, The National Academy Press
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